ESTUDO IN VITRO DA AÇÃO ANTIBACTERIANA DA EUPHORBIA TIRUCALLI LINNEAU EM MICROORGANISMOS ISOLADOS DE DERMATOPATIAS DE CÃES E GATOS.

Abstract

The affections of the integumentary system are important in the small animal clinic. The establishment of a suitable therapy, in bacterial etiology, is impaired when the antibiotic of first choice is not effective and its choice becomes limited the more resistant the bacterium presents. This resistance is a source of concern for veterinary medicine, and improper and abusive use of antibiotics is one of the main causes of the selection of resistant bacteria that has spread worldwide. Among the existent researches, those that aim at bioprospecting with extracts of medicinal plants in bacterial infections, an example of these plants used in popular medicine, but without scientific evidence, is the Euphorbia tirucalli Linneau, popularly known as Avelós. The present work aimed to determine the in vitro antibacterial activity of the plant extracts of the Avelós (Euphorbia tirucalli L.) plant in bacteria, isolated and identified morpho - tintorially, from skin lesions of small animals. Duplicates of Petri dishes (A1 and A2) containing Mueller-Hinton agar were seeded on the surface with bacterial cultures of canine and feline dermatopathies. The agar diffusion method was used by the disc diffusion test inoculating 20 μL of the dilutions of the tested extracts (Latex 100% and Air Part 100%, 80%, 60%) on white discs. Plates were incubated at 37 ° C / 24h. Inhibition halos where available were measured and recorded. The results showed that the extract of Euphorbia tirucalli Linneau presented antimicrobial potential on bacterial growth, with formation of inhibition halos varying from 0.2 to 10.0 mm of diameters. The confirmed antibacterial activity was only for the ethanolic extract of the aerial part, and may be due to the presence of tannins, saponins and flavonoids that have several proven biological applications, although patterns of seasonality seem to have influenced the inhibitory capacity of the latex. These results showed that the use of the ethanolic extract of Euphorbia tirucalli Linneau may be a promising alternative for the control of pathogenic bacterial dermatological microorganisms in the canine and feline medical clinic.