Efeito de aditivos não-antibióticos na dieta inicial de pintainhos de corte desafiados com salmonella enteritidis pós-eclosão

Abstract

The aim of this study was to evaluate the effect of supplementing the initial diet of broiler hatchlings with non- antibiotic additives on Salmonella cecal counts, intestinal morphology and performance after challenge with Salmonella Enteritidis. It was used a fermented compound kind prebiotic (Original XPC, Diamond V) and a phytobiotic based on sanguinarine (Sangrovit, Phytobiotics). A completely randomized experimental design was used according to a 2 x 3 factorial and the following treatments: non-challenged and Salmonella-challenged control x control diet (DCO), diet containing fermented compound type prebiotic (CFP) and diet containing sanguinarine (SAN). The experimental design included 6 treatments, with 22 chicks each. The animals of challenged groups received 0.5 mL of nutrient broth containing Salmonella EnteritidisNal + (SE, 8.3 x 107 CFU/mL) at hatching, while the others received only 0.5 mL of nutrient broth. Supplementation with FCP in the diet reduced (p < 0.05) SE counts in cecal content at 3th day post-inoculation, however, the same effect was not observed at 7th day. Both FCP and SAN reduced the negative effects associated with Salmonella Enteritidis infection on intestinal morphology, especially in birds fed with FCP, demonstrating greater villi height and area, and reduced thickness lamina propria, feature associated with the intestinal inflammation. On the other hand, supplementation with SAN improved animal performance, compared to the other treatments up to 14 days of age. These results demonstrated there is beneficial effects of the investigated products in chicks post-hatching inoculated with Salmonella Enteritidis. The observed beneficial effects differed among the products regarding the observed response. Thus, the physiological mechanisms investigation triggered by composed studies can assist in the strategies development (including using both) focused on reduction of pathogens of interest in public health, in parallel with the improvement of performance, making them alternatives to the use of antimicrobial drugs.