Modelagem da produção de derivados de Vitamina A em biorreatores

Abstract

The objective of this work was the study of bioreactors in fermentative processes of carotenoid production. They used kinetic mathematical models and mass balances for each bioreactor configuration proposed in this study to later apply them to a computational language in the Scilab software. Initially, laboratory methods were used by our research group to obtain experimental data on carotenoids from Rhodotorula glutinis, a microorganism used in fermented media using manipueira as the main substrate. After obtaining the experimental data, it was necessary to determine the correct fit and which mathematical model would be appropriate to better describe the kinetic behavior of our microorganism and to study its fermentative development for each bioreactor configuration studied in this research project. There are numerous models to describe such kinetic behavior, in the literature we selected 4 (four) models, among them we have Monod, which considers only the effects of limiting substrate; Other kinetic models point to inhibition by both substrate and product. Product inhibitions may be represented by Levenspiel, Luong, Ghose and Thyagi models, which proposed substrate and product inhibition in a single equation. The bioreactors used in this study are the fed and non-fed batch, CSTR and PFR that will be presented later in the research project.