COVID-19 e gestação: estudo da transmissão vertical do SARS-CoV-2 no estado da Paraíba

Abstract

After the appearance of the new coronavirus pandemic, several studies have been done about its transmission, which pointed evidence of person-to-person transmission through respiratory secretions, feces, and fomites. However, some evidence questions the possibility of vertical transmission of the virus. Some studies relate the signs of severity and maternal-fetal transmission. This project aims to investigate the possibility of vertical transmission of SARS-CoV-2. The study is a retrospective cohort in the pregnant population of the state of Paraíba. Two groups of pregnant women were analyzed: group I (without signs of severity) and group II (with signs of severity, such as dyspnea and need for ventilatory support). Inclusion criteria were: a positive laboratory diagnosis for COVID-19 by RT-PCR or serological method; being over 18 years of age; and having signed an informed consent form. Exclusion criteria were: lack of accuracy in the date of symptom onset and diagnosis made only by rapid test. The following materials will be analyzed: placenta fragments, umbilical cord, amniotic fluid and umbilical cord blood. The present work was developed during the period of the new coronavirus pandemic, in a context of anticipated completion of health courses throughout the country. In this scenario, the deadline for completion of this project came up against the course completion deadlines, and it is not possible at the moment to present conclusive data.