Correlações anatomoclínicas da osteogênese imperfeita

Abstract

Osteogenesis Imperfecta is a rare pathology characterized by affecting tissues composed of collagen, mainly bone tissue, causing fragility, repetition fractures and skeletal deformities. OI is divided into types and has very varied anatomoclinical characteristics. Human Anatomy is of paramount importance for biological and health sciences. Its multidisciplinary character allows it to be approached through many methods, among them, the practice of anatomoclinical correlations, which aims to study structural and functional alterations of organs and systems. Knowing this, the present study aimed to correlate the types of OI and its anatomical characteristics according to Sillence (1979), in addition to presenting means of diagnosis and treatment to minimize its damage. This is an integrative review carried out in the EBSCO, PubMed and SciELO databases, where, through inclusion and exclusion criteria, 13 articles were gathered to compose the corpus of the work. The articles were divided into two categories: case reports and methods for identifying the clinical characteristics of OI, followed by the presentation of an abstract and subsequent discussion between them. It was concluded that despite the fact that OI has very varied anatomoclinical characteristics, some end up being recurrent, as in the case of fractures by repetition and color of the sclera, lines of research were also perceived that had aspects in common and that there is a clear evolution over the years. themselves, both in the sense of finding out more about the pathology itself, and in the methods of diagnosis and treatment.