Uso da azatioprina no tratamento de trombocitopenia primária (indiopática): Relato de caso

Abstract

Immune-mediated thrombocytopenia is one of the pathologies that affect animals, especially the canine species, especially some breeds such as Cocker Spaniels, Dobermanns and Poodles. It can be primary or secondary, with the primary being the most diagnosed, by excluding the secondary, with titration tests for infectious diseases, physical examination, anamnesis, ultrasounds, radiographs and bone marrow aspirate. The recommended treatment is based on glucocorticoids such as prednisolone in immunosuppressive doses and, in case of non-resolution, other therapies with other immunosuppressants should be initiated, with the use of azathioprine being little reported. The prognosis is reserved to good, as when the animals pass the acute stage of the disease, they tend to improve with proper treatment and management. The present work aims to report a case of primary thrombocytopenia in a poodle dog, in which the treatment with the use of azathioprine was used, observing the improvement and the effectiveness of this drug for immune mediated thrombocytopenia.