Doenças de primatas não humanos de vida livre e em cativeiro no nordeste do Brasil

Abstract

This dissertation was divided into two chapters. The first chapter addresses the diseases that affected non-human primates between the years 2013 and 2020 according to the records of the Veterinary Pathology Laboratory - LPV of the Federal University of Paraíba - UFPB. Nine different primate species were identified. Parasitic diseases were the most prevalent, comprising 22 (40%) cases, followed by bacterial diseases, with 15 (27.3%) cases, neoplastic and viral diseases also had 01 (1.8%) cases each. Traumatic conditions accounted for 7 (12.7%), multifactorial 6 (10.9%), electroplession 2 (3.6%) cases and idiopathic 1 (1.8%) case. Among the parasitic diseases, Molineus torulosus, Trypanoxyuris callitricis, Platynosomum illiciens, Pneumonyssus simicola and Dipetalonema gracile were identified. Isolated bacterial agent was Staphylococcus aureus, Salmonella sp., E. coli and Clostridium sp. Renal adenocarcinoma was the neoplasm identified. The human herpes virus 1 was responsible for the infection. The diversity of diseases identified in different Brazilian and African species reinforces the need for continuous studies to identify the diseases that affect Brazilian primates. The second chapter was a case report describing a fatal case of lowfrequency diseases in non-human primates. An adult male rhesus monkey, coming from the zoo and with no history of previous diseases, presented severe respiratory symptoms with dyspnea, coughing and sneezing. Due to the poor prognosis and non-responsiveness to treatment with anti-inflammatory and antibiotics, euthanasia was chosen. Macroscopically, the lung contained multiple round lesions, sometimes coalescing, yellow to gray, firm, measuring 2 to 5 mm; the kidney contained a rounded, elevated lesion on the capsular surface with a diameter of 0.8 cm, well delimited and white, when cut it was a firm white and rounded surface, limited to the cortical region. Microscopically, there were bronchiolitis and piogranulomatous and eosinophilic bronchitis characterized by multifocal lesions where they replaced and distended the adjacent lung parenchyma due to the large number of neutrophils, macrophages, eosinophils, less multinucleated giant cells, lymphocytes and plasma cells. In the renal cortex, a well-defined circular encapsulated neoplasm was noted, with free margins and densely cellular composed of uniform polygonal cells arranged in papillae supported by thin fibrovascular stroma, immunohistochemistry demonstrated primary malignant epithelial neoplasia. Through the necropsy examination, it was possible to observe two conditions considered low frequency in the rhesus monkey: bronchitis and bronchiolitis due to mites and unilateral renal adenocarcinoma.