Gasometria venenosa em galinhas domesticas (Gallus Gallus Domesticus) submetidas a dois protocolos de contenção quimica

Abstract

The use of opioids, benzodiazepines, and dissociative agents has been a relevant alternative for anesthesia, analgesia, and sedation in birds, especially for quick procedures. This study aimed to evaluate changes in acid–base balance in venous blood samples from 10 healthy domestic chickens subjected to two different chemical containment protocols: CMB Group — ketamine (7 mg/kg), midazolam (0.5 mg/kg), and butorphanol (1 mg/kg); and CMM Group — ketamine (7 mg/kg), midazolam (0.5 mg/kg), and morphine (3 mg/kg). Both protocols were performed in the same animals with a one-week interval between treatments. Samples were collected from the jugular vein before drug administration (baseline — M0) and 15 minutes after intramuscular administration (M1). The data were subjected to statistical analysis using R (R Core Team, 2023). A significant decrease was observed in PO2 and potassium in the CMB group and in lactate in the CMM group. In the between-group comparison, cloacal temperature differed significantly at both time points; sodium, chloride, and ionized calcium at M0; and sodium and PO2 at M1, but without clinical alterations. The remaining parameters showed no statistically significant differences. It was concluded that the protocols used were effective and safe for maintaining the animals’ homeostasis, without inducing electrolyte or acid–base imbalances of clinical relevance.