CARCINOMA DE GLÂNDULA SEBÁCEA EM UMA VACA: RELATO DE CASO

Abstract

The sebaceous gland carcinoma is a malignant neoplasm coming from the skin attachments. It is a nun common neoplasm in dogs and cats and rare in other species. The present study aims to describe a case of the sebaceous gland carcinoma that was diagnosed in a cow at tended at the Veterinary Hospital of the Federal University of Paraíba, located in Areia-PB. A 13-year-old mixed-breed Dutch cow weighing 357 kg, with a history of increased volume associated with a fetid serosanguinolent fistulating injury in the region of the croup above the right ischium one year ago. In the clinical examination, an exoptic, crustous allopathic lesion with hyperkeratosis above the lumbar vertebrae was observed. Complementary exams of hemogram, smear and biopsy were performed. Hematologic analysis showed the following changes: normocytic normochromic anemia in addition to an increase in total plasma proteins (PPT). Blood smear was performed and the following changes were noted, acanthocytes and anisocytosis. The biopsy was performed on exophytic growth located on the animal's back. In the histopathological evaluation was observed a multilobulated mass, nonencapsulated, without free borders, with high cellularity forming separated lobules by connective tissue with periphery constituted by large reserve epithelial cells. In the center of the lobules there are mature sebocytes with intra cytoplasmic lipid vacuoles. The cytoplasm is slightly eosinophilic. Up to five mitosis figures per large magnification field (CGA) are observed. For the treatment the following protocol was indicated: cleaning of the lesion with water and Polyvinylpyrrolidone Iodine in degermante solution (PVPI) associated with the cicatrizing, besides Ketoprofen for pain and Cefquinoma for inflammatory processes. It is concluded that this report is extremely important for the knowledge of clinicians and pathologists of this condition in cattle, since it is unusual for these species.