LÚPUS ERITEMATOSO SISTÊMICO EM CÃO: RELATO DE CASO

Abstract

Systemic lupus erythematosus is an autoimmune pathology, which presents severe clinical signs, among them dermatopathies. Its etiology is not yet established, it is a rare disease and affects dogs and cats. High levels of circulating autoantibodies indicate that the defect of systemic lupus erythematosus occurs due to failure of the mechanisms responsible for tolerance to either the B lymphocyte, T lymphocyte or both. There is a change in the maturation process and the auto-reactive lymphocytes become mature and can be activated and initiate autoimmunity. The present study aimed to report the case of a systemic lupus erythematosus in a dog, of seven months, who was submitted to a veterinary hospital of the Federal University of Paraíba. The animal had anemia, hyperthermia, skin lesions, joint edema, lameness. Diagnosis was based on clinical signs, histopathological and hematological findings. For treatment prednisolone dose of 2 mg / kg was initially prescribed orally, essential fatty acids and 10% urea moisturizing cream, 0.3% hydrocortisone, 5% Aloe vera. There was no total remission of the lesions and, in an attempt to decrease the dose of prednisolone, clinical signs recurred, remaining at a dose of 1 mg / kg daily.