Nefropatia medicamentosa em bezerros atendidos no hospital veterinário da Universidade Federal da Paraíba

Abstract

Renal disorders are not among the most reported pathologies in ruminants in general. However, when affected, the patient's prognosis becomes reserved for unfavorable, considering the various functions performed by them. Therefore, knowledge about clinical signs, laboratory, histological and necropsy findings, mechanisms of injuries is necessary for new cases to be avoided. This work aimed, initially, to present a theoretical reference on the anatomical, physiological, semiological, clinical-pathological and histological aspects of injuries caused by some non-steroidal antibiotics and anti-inflammatory drugs. Clinical records and necropsy reports of three animals seen at the Veterinary Hospital of the Federal University of Paraíba with a diagnosis of kidney disease were analyzed. The clinical and histological findings of the animals analyzed were quite similar to each other and characteristic of renal tubular injury, such as polyuria, polydipsia and anemia in more chronic conditions, the histological findings showed marked diffuse pallor of the renal parenchyma and tubular necrosis with detachment of cells tubular to their lumen. Through the findings, it was possible to suggest that the clinical condition of the animals was related to the indiscriminate use of the aforementioned drugs.