Implantes hormonais e terapia de reposição hormonal na menopausa: Uma revisão de literatura

Abstract

In an attempt to relieve symptoms during menopause, several methods have been adopted for hormone replacement therapy, with emphasis on the route of administration performed through subcutaneous hormonal implants. Therefore, the present study aims to investigate the effectiveness of using implants in hormone replacement therapy in menopause and post menopause, as well as the intrinsic risks of these procedures. To this end, a systematic review of the literature present in the BVS / MEDLINE in the last 15 years was carried out, selecting 5 articles. Among the results obtained, there is a retrospective study of 258 women using estradiol and testosterone implants, an open parallel study with 40 women, of which 20 of them used estradiol implants and 20 using estradiol implants + nomegestrol acetate, another study prospective cohort with 61 women, 34 using estradiol and testosterone implants and 27 without implants, a prospective cohort with 122 women divided into three specific groups, and lastly a retrospective clinical audit on 114 women using estradiol implants. Thus, it became possible to verify that there is a scarcity of studies for this purpose, in addition to the heterogeneity of these publications, which causes limitations of evidence for their use in clinical practice. However, the available results are favorable in the prevention and treatment of conditions resulting from climacteric and menopause.