Insulinoma em cão portador de hipercortisolismo - Relato de casso

Abstract

Insulinoma is a pancreatic ß-cell tumor that presents functionally secreting high levels of insulin, causing hypoglycemic crisis that can lead to the animal's death. The clinical signs of this neoplasm are nonspecific and the most frequent ones are weakness, seizures, mental and behavioral changes, all of which are not very enlightening for the diagnosis. The association of clinical manifestations, laboratory evidence of hypoglycemia and hyperinsulinemia, and imaging tests, provides the clinician with a presumptive diagnosis of insulinoma. However, the definitive diagnosis depends on the histopathological evaluation of the neoplasm after its surgical resection. Surgical removal of insulinoma is a therapeutic measure that allows for greater patient survival; however, pharmacological and dietary treatment must be present aiming at the animal's quality of life. The objective of this work is to carry out a brief literature review on the subject, as well as to report a clinical case of a hyperadrenocorticoid dog that developed an insulinoma, which has been successfully treated clinically.