EFEITOS DA VACINAÇÃO PARA COVID-19 EM PACIENTES COM URTICÁRIA CRÔNICA - UCARE PARAÍBA

Abstract

Background: Chronic urticaria is defined as the appearence of either characteristic skin lesions, angioedema or both. Urticaria lesions consists of discrete áreas of skin edema that are usually pruritic and transitory, disappearing in 24 hours or less. It’s physiopathology is associated with a wide variety of stimuli through different mechanisms, and has been described in the literature as a reaction to some forms of vacciantionn .Objectives: This study aims to observe the freqeuency, risk factors and clinical characteristics of the COVID19 vaccine in patients with chronic urticaria. Metods: This is a cross-sectional study, and the data was colected through a survey instrument made for this research. It was Applied to patients with chronic urticaria in the waiting room of UCARE-PB. Results: This study obtained a sample of 44 patients, ages raging from 20 to 80 years old and a mean of 43 years old, from which 8 (18,1%) observed worsening of their condition after at least one dose of imunization. Most patients had the reaction within 7 days. Patients also described using anti histamines, corticosteroids and analgesics to deal with the effects, and mosto f them (5 patients) reported good resultis within 5 days or less. There were 2 cases where the patients referred that the urticaria exacerbation lasted for 28 days and 5 months, despise adequate treatement. Conclusion: In this study, 18,1% patients described worsening of the chronic uritcaria after at least one COVID19 vaccination.