Dinâmica de expressão de interleucinas no intestino de pintainhos de diferentes linhagens desafiados com salmonella enteritidis

Abstract

The objective of this study was to evaluate the behavior of interleukins in poultry commercial and neck naked challenged Salmonella Enteritidis challenged. A total of 200 eggs from the Cobb500® and Label Rouge® lines were used in the incubation, of these 100 chickens were used in the experiment. The evaluations were performed in the pre-initial phase (1-9 days). The parameters analyzed were bacterial count (CFU / mL) and relative expression of interleukins (IL-1, IL-8, IL-17 and IL-22). The animals were arranged in a completely randomized design (CRD) with 25 replicates, forming 4 treatments: Cobb500® line without challenge of Salmonella after hatching (Cobb-SS); Cobb500® line and challenge with post-hatching Salmonella (Cobb-CS); Label Rouge® line without challenge of Salmonella after hatching (LR-SS); Label Rouge® line and post-hatch Salmonella challenge (LR-CS). The Cobb500® line presented higher cecal bacterial counts in the period of 168 hpi. The different genotypes use differentiated routes in the two challenge situations, Label Rouge® is linked to the cytokines that are expressed by heterophiles. The relative expression of interleukins showed that there is a different dynamics between the lines. The Label Rouge® line shows earlier development of tolerance to S. Enteritidis than the Cobb500® lineage.