ANÁLISE DA QUALIDADE DE VIDA EM PACIENTES COM HIPERPARATIREOIDISMO SECUNDÁRIO À DOENÇA RENAL CRÔNICA EM TERAPIA DE HEMODIÁLISE

Abstract

Secondary hyperparathyroidism is a common complication in patients with chronic kidney disease on hemodialysis. Although the phyosiopathology is still not completely elucidated, the clinical presentation is well known and despite therapeutic advances, a cure through clinical management is still not a reality. Given the lack of prospects for a cure through clinical management, the quality of life of these patients should be prioritized. This study aims to objectively analyze the quality of life of patients on hemodialysis with secondary hyperparathyroidism caused by chronic kidney disease, in comparison to their parathyroid hormone levels. The chosen methodology is a observational, cross-sectional, non-controlled study, with statistical analysis using the Short Form 36 Health Survey Questionnaire and the parathormon levels suggested by the Kidney Disease Outcomes Quality Index guideline. The results showed statistical significance in three out of ten parameters measured by the questionnaire, those being functional capacity, pain and physicial component. Mental health related items did not obtain statistical significance, but did show a favorable tendency towards the group with proper control of parathormon. These results regarding the physicial aspects were expected, as they are similar to the results of studies regarding surgical intervention through parathyroidectomy. But the results of the mental health related items were not expected. It is possible that the SARS-CoV-2 pandemic may have played an important role as a confounding variable, as there is vast documentation of its negative impact on the mental health throughout the world. These findings provide important information to the clinical manegement of patients with hyperpathyroidism secondary to chronic kidney diasease requiring hemodialysis.