Avanços na farmácia magistral veterinária: desenvolvimento de formulações para pets no contexto atual

Abstract

The veterinary compounding pharmacy is the area of pharmacy that handles personalized medications for animals. Brazil ranks third in the global pet market, behind only the United States and China. In 2023, the sector had revenues of approximately R$47 billion, of which 15% corresponded to veterinary medications. In addition, the country has one of the largest populations of domestic animals in the world, with estimates indicating 67.8 million dogs and 33.6 million cats in 2022. The personalization of medications allows for the adjustment of doses, pharmaceutical forms, and palatability, contributing to better adherence to treatment. Therefore, this study aimed to conduct a bibliographic survey on new formulations for pets between the years 2021 and 2024. The elucidations were obtained from the Pubmed, Google Scholar, Scielo, and Elsevier databases. Three new studies were chosen, namely, orodispersible films (ODFs) containing chlorhexidine digluconate (DC) for use as an adjuvant in oral hygiene of dogs, veterinary biscuits as a pharmacotherapeutic alternative for small dogs with osteoarthritis and veterinary shampoo containing Borago officinalis oil in the prevention of canine dermatitis. The ODFs underwent quality control and in vitro antimicrobial efficacy tests that demonstrated their potential use in veterinary practice. The veterinary biscuits underwent all production stages following good handling practices standards and presented a homogeneous final product with a light brown color, which is a positive indication in the handling of the formulation. The veterinary shampoo underwent all stability and safety tests and was used for testing in dogs with pruritus, in which they showed improvement in skin appearance and reduction of pruritus. The formulations proved to be promising and innovative, but further studies are needed to prove the efficacy and safety of the chosen formulations.