Vigilância de medicamentos e produtos para saúde em um hospital municipal de João Pessoa-PB: uma análise das notificações feitas através dos sistemas vigimed e notivisa

Abstract

Surveillance is an essential service in healthcare, especially in hospital environments, where it represents a breeding ground for health product failures and adverse drug events. In Brazil, the Health Surveillance Agency (Anvisa) plays a crucial role in this context, as it is the body responsible for overseeing companies, industries, borders and ports, as well as controlling all active pharmaceutical ingredients in the country, i.e. the raw materials needed to manufacture medicines. To improve this surveillance, Anvisa created the sentinel hospitals, a strategy that emerged in 2001, which is made up of a national network of hospitals designed to monitor products and medicines, guaranteeing quality and patient safety. The network of sentinel hospitals covers pharmacovigilance, technovigilance and hemovigilance, and acts through notifications made by health professionals, either spontaneously or through active searches. These reports are essential for identifying and resolving problems. They contain information on technical complaints, such as deviations in the quality of materials, and adverse reactions about drugs. This study is an observational, descriptive, and crossectional analyzes data from notifications made by the Cândida Vargas Institute, a municipal hospital in João Pessoa, registered on VigiMed and Notivisa between January 2023 and July 2024. The aim of the study is to quantify, evaluate, and understand the profile of notifications, highlighting the importance of sentinel hospitals and health surveillance, as well as raising awareness among professionals about the necessity of making notifications. The total of 85 notifications were analyzed, with the majority stemming from active searches (58%). Furthermore, the reported issues were categorized according to hemovigilance (n=4), technovigilance (n=12), and pharmacovigilance (n=69). The pharmacovigilance errors included medication dispensing errors (n=4), prescription errors (n=16), and medication administration errors (n=45), with adverse reaction cases totaling (n=4). Therefore, medication administration errors were the most frequently observed, primarily arising from nursing professionals' mistakes. This underscores the need for better training for healthcare professionals, as well as the importance of surveillance in the hospital environment to ensure patient safety.