Desenvolvimento de protetor solar em stick fps 30 com aciclovir para o tratamento de infecção pelo vírus hsv-1

Abstract

Advances in technology have driven the need to develop new cosmetic formulations that incorporate pharmaceutical actives, such as Acyclovir, a drug used in the treatment of infections caused by HSV-1 and HSV-2. The objective of this study was to develop and evaluate the preliminary stability of a sunscreen stick with SPF 30 containing acyclovir in suspended form. The preparation of the sticks followed a three-phase procedure involving phases of high heating and cooling below 40°C and bottling of the product while still hot. The experiments were carried out at the Research and Development Laboratory of the Alianza Cosmetic Industry, including stability tests with analysis of organoleptic characteristics and simulation of sun protection. The results indicated that all formulations were stable, and all samples were approved in the organoleptic evaluations. The product demonstrated an estimated final SPF of 30 and UVA protection of 16.9, exceeding regulatory requirements. These results highlight the good potential of the product for commercialization, offering not only sun protection, but also treatment of lesions caused by HSV-1.