Tumor testicular misto em cão: relato de caso.

Abstract

Testicular neoplasms are common in older dogs, and less common in other domestic species. Among the various histological types, Leydig cell tumor, seminoma and sertolioma, are the main primary neoplasms reported in order of occurrence and may appear alone or associated, unilaterally or bilaterally. Approximately 40% of dogs that develop testicular neoplasms have more than one type of tumor called mixed tumors, which are unique and include a mixture of different neoplastic cells. The aim of this study was to report a case of unilateral mixed testicular tumor in a ten-year-old mixed breed dog. The animal was treated at the Veterinary Hospital of the Federal University of Paraíba with a history of penile bleeding. Physical examination revealed enlargement of the left testis, prostatic enlargement and moderate hematuria. Hematological examinations, ultrasonography and testicular cytology were requested. Significant findings were observed only in cytology being consistent with sertolioma. The animal was referred to surgery for ablation of the testicles that subsequently underwent histopathological evaluation, which revealed cell characteristics suggestive of Leydig cell tumor and sertolioma. An immunohistochemical study was performed with the markers Melan A, GATA-4, Alpha-inhibin, CD117 positive for Leydig cells and PGP9.5 positive for seminoma. Given this, it is possible to recognize the importance of differentiation through antibodies in immunohistochemistry, because from this it is possible to evidence characteristics of the tumor that in histopathology were not conclusive.