Hipoadrenocor2cismo em cão: Relato de

Abstract

Hypoadrenocorticism is an endocrinopathy characterized by glucocorticoid deficiency, either isolated or associated with mineralocorticoid deficiency, whose diagnosis is hindered by nonspecific and progressive clinical signs. In severe cases, it may progress to adrenal crisis with severe hydroelectrolytic disturbances. This report describes the case of a 12-year-old male Pug that presented with a history of refractory chronic vomiting, hyporexia, polyuria, and weight loss. During the diagnostic investigation, laboratory tests revealed biochemical and hematological values within normal ranges, except for an inadequate sodium/potassium ratio, although serum electrolytes remained within reference limits. The definitive diagnosis was established through the ACTH stimulation test, which confirmed low cortisol production. Treatment with glucocorticoid and mineralocorticoid replacement led to clinical improvement through dose adjustments based on laboratory results. Since then, the patient has been monitored monthly, with laboratory tests for electrolyte assessment and follow-up of the therapeutic response. This case reinforces that the early diagnosis of hypoadrenocorticism, combined with continuous electrolyte monitoring and individualized adjustment of hormonal therapy, is essential for clinical control and improvement of the prognosis in dogs affected by this endocrinopathy.