Treinamento resistido em idosos e liberação de miocinas: uma revisão integrativa

Abstract

Muscle strength is essential for the health and quality of life of the elderly, since as age advances, the relative loss of strength affects the ability to perform daily activities, being associated with the impairment of both physical and cognitive aspects. The objective of this integrative review was to demonstrate how the practice of physical activities, especially resistance exercise, and the consequent release of myokines can benefit the health of the elderly, observing the scientific literature. The review considered research collected from December 2024 to March 2025, in the CAPES Portal, with the search argument “myokines AND elderly” and time filters between 2010 and 2025, in Portuguese, English and Spanish, for peer-reviewed publications, having found 10 articles for analysis. It was found that most of the articles analyzed addressed the effects of physical exercise on brain, muscle and metabolic health. The myokine irisin was the most cited, with positive effects on muscle strength, cognition and synaptic plasticity. Biomarkers such as interleukin-6 (IL-6) also stood out. Resistance training, alone or combined with aerobic exercise, demonstrated improvement in mitochondrial function, reduction of inflammation and prevention of sarcopenia in the elderly. It is concluded that regular practice of resistance exercise stimulates the release of myokines with beneficial effects on muscular and cognitive health, being an effective strategy in promoting quality of life in old age