USO DE CÉLULAS TRONCO AUTÓLOGAS DE TECIDO ADIPOSO EM CÃO COM APLASIA MEDULAR (RELATO DE CASO)

Abstract

Medullary aplasia (also known as aplastic anemia) is relatively rare in dogs and cats and is characterized by peripheral blood pancytopenia and hypoplasia of three cell lines (erythroid, myeloid and megakaryocytic) in the bone marrow, resulting in the replacement of hematopoietic tissue by adipose tissue. There is also a classification according to the presentation and evolution of cytopenias in peripheral blood and medullary hypoplasia, characterizing aplasia as acute or chronic. The aim of the present study was to report the treatment with stem cells for pancytopenia caused by canine Erythiliasis, in dogs of 4 years and 6 months of age, weighing 10.6kg in a veterinary clinic - Campina Grande, PB. During the first clinical evaluation, pale ocular and oral mucosa, severe dermatitis, slightly anorexic, and according to her guardian with diagnosis of canine Erythemia elucidated in another clinic were observed. Therefore, new complementary exams such as hemograms were used, which always resulted in regenerative hypochromic microcytic anemia, leukopenia with leukopenia due to lymphocytopenia, absolute degenerative monocytopenia, and in thrombocytopenia, biochemical with normal results, indirect immunofluorescence for distemper, urinalysis, and hematopoietic screening. In the hematozoan research the presence of Erlichia spp. In the patient's lymphocytes. Faced with this diagnosis. The following treatment was instituted, Omeprazole, Doxycycline, Nutritional Supplement, Timerovac, ivermectin and chlorhexidine 3g. However the treatment did not result in improvement, a new treatment was chosen using a stem cell implant, produced from the animal's own adipose tissue. But the animal died from cardiorespiratory arrest. Therefore, new studies in this area are of great importance for new discoveries that come to seek treatment and alternatives for dogs with chronic Erythroblastoma. The objective of this study was to describe a case of a dog with chronic canine Erliquiosis treated with stem cells.